Approved Dosage Form & Strength
- Dosage Form: Extended Release Tablets
- Strength: 82.5 & 165 mg
For Treatment of Peripheral Neuropathic Pain Associated with Diabetic Peripheral Neuropathy
Begin dosing at 165 mg once daily and increase to 330 mg once daily within 1 week based on individual patient response and tolerability. The maximum recommended dose of is pregabalin extended release tablets 330 mg once daily. Although pregabalin were studied at 600 mg/day, there was no evidence that this dose conferred additional significant benefit and this dose was less well tolerated. In view of the dose-dependent adverse reactions with pregabalin, treatment with doses above 330 mg/day is not recommended for pregabalin extended release tablets.
For Treatment of Peripheral Neuropathic Pain of Post herpetic Neuralgia
Begin dosing at 165 mg once daily and increase to 330 mg once daily within 1 week based on individual patient response and tolerability. Patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 330 mg once daily and who are able to tolerate pregabalin extended release tablets, may be treated with up to 660 mg once daily. In view of the dose-dependent adverse reactions and the higher rate of treatment discontinuation due to adverse reactions, dosing above 330 mg/day should be reserved only for those patients who have on-going pain and are tolerating 330 mg daily. The maximum recommended dose of pregabalin extended release tablets is 660 mg once daily.